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Although, in this review article, we focused on abiotic stress-induced oxidative damage and the role of AsA-GSH cycle to mitigate such adversities, biotic stress (fungi, bacteria, virus, nematodes, and parasitic organisms, etc.) might also alter the essential plant processes as well as cellular metabolism.For example, the production of ROS and oxidative stress, disruption of membranes, hampering photosynthesis, changing enzyme activities, cell death, and yield loss might also be attributed to biotic stress, which is in line with abiotic stress.Biotic stress also disrupts signal transduction, as well as transfigures signal pathways that are associated with stress acclimation