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Thus, HGF, as a paracrine factor, may contribute to successful stem-cell-based therapies, which have been investigated in many clinical trials in the context of pathologies such as SCI, PD, ALS, AD, and MS with promising results (Jafarzadeh Bejargafshe et al., 2019

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Second, peroxiredoxins (Prx), are highly abundant in the cytosol and have exceptionally nucleophilic active site Cys residues that react with H 2 O 2 at rates ~10 7 -fold faster than most protein-Cys residues [168, 169]