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RNA isolation and quantitative real-time PCR Skeletal muscle samples from the gastrocnemius muscles were homogenized in 1.5 mL Eppendorf ® tubes with tungsten carbide and micro-glass beads using a TissueLyser LT system (Qiagen, USA) pre-cooled to − 80 °C

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Interestingly, Scutellaria baicalensis Georgi not only enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced AKI [87]