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Monosodium glutamate exacerbated the lipopolysaccharide-induced reproductive toxicity of male Wistar rats | BMC Pharmacology and Toxicology | Springer Nature Link

Detailed Molecular Information: Molecular Formula: C₆₂H₉₈N₁₆O₂₂ Molecular Mass: 1419.5 daltons CAS Number: 137525-51-0 Sequence: GEPPPGKPADDAGLV (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) Number of Amino Acids: 15 Isoelectric Point (pI): Approximately 4.5-5.0 Full Sequence Breakdown with Properties: Structural Features: Linear pentadecapeptide (15 amino acids) Contains three consecutive prolines (positions 3-5) — creates structural rigidity Contains multiple negatively charged residues (glutamic acid, aspartic acid) Contains positively charged lysine Hydrophobic C-terminus (leucine, valine) No disulfide bonds or cyclic structures The cluster of three consecutive prolines (Pro-Pro-Pro) is a notable structural feature

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During this period, the patient also experienced a reduction in TDD of insulin (from about 45 units/day pre-tirzepatide therapy to about 46 units/day)