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Figure 7 Despite encouraging findings from experimental and preclinical studies, the clinical translation of antioxidant-based therapies remains complex and, in some cases, inconsistent

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138 Park et al also targeted BACE1 with CRISPR-Cas9 ribonucleoproteins (RNPs) using amphiphilic peptide (R7L10), lowering Aβ plaque formation and alleviating cognitive deficits in AD mouse models