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reported significant improvements in ALT and 8-OHdG only in NASH patients, while the NAFL group showed only nonsignificant reductions [102]

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Research Applications Obesity and body weight regulation research Type 2 diabetes and glycemic control studies Appetite and satiety pathway research Amylin and GLP-1 receptor signaling studies Gastric emptying and postprandial glucose research Combination peptide pharmacology studies Energy intake and food reward research Cardiometabolic risk factor studies Hypothalamic appetite circuit research Comparative metabolic peptide studies Safety Profile The safety profile of the cagrilintide + semaglutide blend draws on the substantial individual safety datasets for each peptide as well as growing combination data from Phase 1b and Phase 2 clinical research