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Since nitrous oxide is commonly used for surgery in the elderly, some experts feel vitamin B 12 deficiency should be ruled out prior to its use or prophylactic vitamin B 12 supplementation implemented before and after exposure to the gas (7, 18)

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The weight loss marketing around “B12 shots” almost always refers to lipotropic blends containing carnitine, methionine, and choline, and the evidence that those cause meaningful fat loss without diet changes is weak