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It is important to emphasise that these proposals are based almost entirely on preclinical data — principally in vitro (cell culture) experiments and animal studies — and have not been reliably demonstrated in robust human clinical trials: Stimulation of follicle enlargement: Laboratory studies suggest GHK-Cu may increase hair follicle size, potentially counteracting the miniaturisation associated with androgenetic alopecia (pattern hair loss), though this has not been confirmed in humans