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84 In contrast, MPTP treatment reduces TH-positive neurons, decreases concentrations of dopamine as well as its metabolites 3,4-dihydroxyphenylacetic acid and homovanillic acid, and increases the ratio of dopamine metabolites to dopamine
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Conversely, in the reverse testing scenario, these metrics dropped by 12.2 points, 18.9 points and 8.9 points, respectively
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