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SKU: 62142323217
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Amyloid beta-peptide increases mitochondria-endoplasmic reticulum contact altering mitochondrial function and autophagosome formation in alzheimer's disease-related models

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This calcium influx induces mitochondrial Ca 2+ overload and ROS bursts, promoting abnormal opening of the mitochondrial permeability transition pore (mPTP) and amplifying the lipid peroxidation cascade (Yang et al., 2015)

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