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Frontiers | How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

Meanwhile, glutamine modulates autophagy through the production of glutathione and NADPH, which affect ROS levels (106)

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however, zinc supplementation (300 mg zinc aspartate, equal to 60 mg elemental zinc per day for 4 weeks) in 14 zinc-deficient patients with IBD resulted in slightly higher metallothionein concentration in the intestinal mucosa [196]